Trem2 - RNA Expression

 

Trem2 - Gene Information

Name: triggering receptor expressed on myeloid cells 2
Aliases: triggering receptor expressed on myeloid cells 2c, triggering receptor expressed on myeloid cells 2a, triggering receptor expressed on myeloid cells 2b, Trem2c, Trem2b, Trem2a
Description: PHENOTYPE: Mice homozygous for a knock-out allele display enhanced cytokine production by macrophages in response to toll-like receptor agonists. Mice homozygous for a different knock-out allele show reduced microglial cell survival, proliferation and activation and cell cycle arrest at the G1/S checkpoint. [provided by MGI curators]
Crossreferences: MGI:1913150, ENSEMBL:ENSMUSG00000023992, NCBI_Gene:83433, UniProtKB:Q99NH8, UniProtKB:Q3U2Q4
This information is supplied by the AllianceGenome.org API.
 

Trem2 - Differential Expression

Ly6CHigh Blood Monocytes

Compared To: Log2fold: SEM: Adjusted p-value:
Ly6CLow Blood Monocytes 1.0307 0.3665 0.047235440766035
Ly6CHigh Brain Monocytes -1.8229 0.3578 9.11E-6
CCR2High Brain Macrophages -2.5582 0.3351 1.4553750760006E-12
CCR2Low Brain Macrophages -3.039 0.335 1.25E-17

Ly6CLow Blood Monocytes

Compared To: Log2fold: SEM: Adjusted p-value:
Ly6CHigh Blood Monocytes -1.0307 0.3665 0.047235440766035
Ly6CHigh Brain Monocytes -2.8536 0.3625 3.25E-13
CCR2High Brain Macrophages -3.5889 0.34 1.05E-23
CCR2Low Brain Macrophages -4.0697 0.3399 <= 1.0E-32

Ly6CHigh Brain Monocytes

Compared To: Log2fold: SEM: Adjusted p-value:
Ly6CHigh Blood Monocytes 1.8229 0.3578 9.11E-6
Ly6CLow Blood Monocytes 2.8536 0.3625 3.25E-13
CCR2High Brain Macrophages -0.7353 0.3307 0.57440286
CCR2Low Brain Macrophages -1.2161 0.3306 0.014513846

CCR2High Brain Macrophages

Compared To: Log2fold: SEM: Adjusted p-value:
Ly6CHigh Blood Monocytes 2.558 0.335 1.46E-12
Ly6CLow Blood Monocytes 3.589 0.34 1.05E-23
Ly6CHigh Brain Monocytes 0.7353 0.3307 0.57440286021996
CCR2Low Brain Macrophages -0.4808 0.3057 1

CCR2Low Brain Macrophages

Compared To: Log2fold: SEM: Adjusted p-value:
Ly6CHigh Blood Monocytes 3.039 0.335 1.25E-17
Ly6CLow Blood Monocytes 4.0697 0.3399 2.0E-30
Ly6CHigh Brain Monocytes 1.2161 0.3306 0.014513846
CCR2High Brain Macrophages 0.4808 0.3057 1