Siglece - RNA Expression

 

Siglece - Gene Information

Name: sialic acid binding Ig-like lectin E
Aliases: Siglec5, mSiglec-E, sialic acid binding Ig-like lectin 5, Siglecl1, SIGLEC-like 1
Description: PHENOTYPE: Mice homozygous for a knock-out allele or a knock-in allele that destroys the sialic acid binding site exhibit increased neutrophil and macrophage recruitment in an LPS-induced model of acute lung ariway inflammation. [provided by MGI curators]
Crossreferences: MGI:1932475, UniProtKB:A0A0U1RPP9, UniProtKB:Q6PJ50, UniProtKB:Q91Y57, NCBI_Gene:83382, ENSEMBL:ENSMUSG00000030474
This information is supplied by the AllianceGenome.org API.
 

Siglece - Differential Expression

Ly6CHigh Blood Monocytes

Compared To: Log2fold: SEM: Adjusted p-value:
Ly6CLow Blood Monocytes 0.9493 0.55 0.28051269285633
Ly6CHigh Brain Monocytes 0.7357 0.5511 0.458588052
CCR2High Brain Macrophages 0.3013 0.5168 0.76179940347906
CCR2Low Brain Macrophages 0.3958 0.5174 0.670638286

Ly6CLow Blood Monocytes

Compared To: Log2fold: SEM: Adjusted p-value:
Ly6CHigh Blood Monocytes -0.9493 0.55 0.28051269285633
Ly6CHigh Brain Monocytes -0.2136 0.5526 0.833940727
CCR2High Brain Macrophages -0.648 0.5184 0.388630764
CCR2Low Brain Macrophages -0.5535 0.5189 0.473131514

Ly6CHigh Brain Monocytes

Compared To: Log2fold: SEM: Adjusted p-value:
Ly6CHigh Blood Monocytes -0.7357 0.5511 0.458588052
Ly6CLow Blood Monocytes 0.2136 0.5526 0.833940727
CCR2High Brain Macrophages -0.4344 0.5196 1
CCR2Low Brain Macrophages -0.3398 0.5201 0.973422389

CCR2High Brain Macrophages

Compared To: Log2fold: SEM: Adjusted p-value:
Ly6CHigh Blood Monocytes -0.301 0.517 0.761799403
Ly6CLow Blood Monocytes 0.648 0.518 0.388630764
Ly6CHigh Brain Monocytes 0.4344 0.5196 1
CCR2Low Brain Macrophages 0.0946 0.4834 1

CCR2Low Brain Macrophages

Compared To: Log2fold: SEM: Adjusted p-value:
Ly6CHigh Blood Monocytes -0.3958 0.5174 0.670638286
Ly6CLow Blood Monocytes 0.5535 0.5189 0.473131514
Ly6CHigh Brain Monocytes 0.3398 0.5201 0.973422389
CCR2High Brain Macrophages -0.0946 0.4834 1